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Substituted pyrrolidin-2-ones: Centrally acting orexin receptor antagonists promoting sleep. Part 2

Thierry Sifferlen1, Amandine Boller1, Audrey Chardonneau1

  • 1Actelion Pharmaceuticals Ltd, Drug Discovery and Preclinical Research & Development, Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.

Bioorganic & Medicinal Chemistry Letters
|April 4, 2015
PubMed

Keywords:
CNS drug discoveryDual orexin receptor antagonistsMetabolic stabilityOrexin receptorsSelective orexin-2 receptor antagonistsSleep

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