Related Experiment Video
Updated: Apr 15, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
Domestic use of bleach and infections in children: a multicentre cross-sectional study
Lidia Casas1, Ana Espinosa2, Alícia Borràs-Santos3
1Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain University Pompeu Fabra (UPF), Barcelona, Spain.
Insights
Home bleach use is linked to increased infections in children. Passive exposure to cleaning products may raise risks for respiratory and other illnesses, posing a public health concern.
Area of Science:
- Environmental Health
- Pediatric Health
- Epidemiology
Background:
- Household cleaning products, particularly bleach, are widely used globally.
- Concerns exist regarding the potential health impacts of chemical exposures in indoor environments.
- Previous research has not fully elucidated the association between domestic bleach use and childhood infection rates.
Purpose of the Study:
- To investigate the relationship between household bleach usage and the incidence of various infections in school-aged children.
- To quantify the risk of infections associated with passive exposure to cleaning bleach at home.
Main Methods:
- A cross-sectional study involving 9102 school-aged children (6-12 years) across Spain, the Netherlands, and Finland.
- Parental questionnaires collected data on infection frequency (influenza, tonsillitis, sinusitis, otitis, bronchitis, pneumonia) and home bleach use.
- Multivariable mixed-effects regression models and random-effects meta-analyses were employed to assess associations.
Main Results:
- Bleach use varied significantly by country, being most common in Spain (72%) and least common in Finland (7%).
- Children in households using bleach exhibited a higher prevalence of infections.
- Significant associations were found between bleach use and increased risk for influenza (once), recurrent tonsillitis, and any infection.
Conclusions:
- Passive exposure to household cleaning bleach may negatively impact school-aged children's health.
- Increased risk of respiratory and other infections is associated with domestic bleach use.
- The widespread use of disinfecting cleaning agents warrants public health attention due to potential childhood health risks.
Objective:
To report the effects of bleach use at home on the frequency of infections in 9102 school-age children participating in the HITEA project.
Methods:
Parents of pupils aged 6-12 years from schools in Barcelona province (Spain), Utrecht province (the Netherlands) and Eastern and Central Finland were administered a questionnaire including questions on the frequency of infections (influenza, tonsillitis, sinusitis, otitis, bronchitis and pneumonia) in the past 12 months and bleach use at home. We developed multivariable mixed-effects multilogistic regression models to obtain relative risk ratios (RRR) and their 95% CI per country, and combined the RRR using random-effects meta-analyses.
Results:
Bleach use was common in Spain (72%, n=1945) and uncommon in Finland (7%, n=279). Overall, the prevalence of infections (recurrent or once) was higher among children of bleach users. Significant combined associations were shown for influenza only once (RRR=1.20, 95% CI 1.04 to 1.38), recurrent tonsillitis (RRR=1.35, 95% CI 1.07 to 1.71) and any infection (RRR=1.18, 95% CI 1.01 to 1.38).
Conclusions:
Passive exposure to cleaning bleach in the home may have adverse effects on school-age children's health by increasing the risk of respiratory and other infections. The high frequency of use of disinfecting irritant cleaning products may be of public health concern, also when exposure occurs during childhood.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Hand hygiene
Hand washing...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Development of Human Microbiota
Cleaning, Sterilization, and Disinfection
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Development of the Oral Microbiota

