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Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injury

Anita Kása1, Csilla Csortos2, Alexander D Verin3

  • 1Vascular Biology Center; Georgia Regents University ; Augusta, GA USA.

Tissue Barriers
|April 4, 2015
PubMed

Keywords:
AJ, adherens junctionALI, Acute Lung InjuryARDS, Acute Respiratory Distress SyndromeCPI-17, PKC potentiated inhibitory protein of 17 kDaCaD, caldesmonEC, endothelial cellsGJ, gap junctionHSP-27, small heat shock actin-capping protein of 27 kDaIL, interleukinLPS, lipopolysaccharideMLC, myosin light chainMLCK, Ca2+/calmodulin (CaM) dependent MLC kinaseMLCP, myosin light chain phosphataseMT, microtubulesMYPT1, myosin phosphatase targeting subunit 1PKA, protein kinase APKC, protein kinase CSM, smooth muscleTJ, tight junctionTLR4, toll-like receptor 4TNFα, tumor necrosis factor αacute lung injurybarrier functioncytoskeletonendothelial junctionspulmonary endotheliumthrombin

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