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Published on: September 8, 2021
Protective effects of bacterial osmoprotectant ectoine on bovine erythrocytes subjected to staphylococcal
Adam Bownik1, Zofia Stępniewska2
1Department of Animal Physiology and Toxicology, Faculty of Biotechnology and Environmental Sciences, The John Paul II Catholic University of Lublin, Kontstantynów 1 "I", 20-708 Lublin, Poland.
Abstract:
Ectoine (ECT) is a bacterial compatible solute with documented protective action however no data are available on its effects on various cells against bacterial toxins. Therefore, we determined the in vitro influence of ECT on bovine erythrocytes subjected to staphylococcal α-haemolysin (HlyA). The cells exposed to HlyA alone showed a distinct haemolysis and reduced glutathione (GSH)/oxidised glutathione (GSSG) level, however the toxic effects were attenuated in the combinations of HlyA + ECT suggesting ECT-induced protection of erythrocytes from HlyA.
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