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How many drugs in the maintenance setting for non-small-cell lung cancer? For what benefit?
1Service de Pathologie Respiratoire CHU Dupuytren, Hôpital du Cluzeau, 87042 Limoges cedex, France. alain.vergnenegre@unilim.fr.
Annals of Palliative Medicine
|April 6, 2015
Abstract:
Maintenance treatment has been used for several years inside clinical trials. Meta-analyses have been published. A new clinical trial (AVAPERL) has been recently published. Despite significant increase of progression-free survival (PFS), overall survival (OS) has not been changed with these strategies. Before a transfer into clinical practices and guidelines, new data on economic analyses (the cost effectiveness ratio was very high among specific studies) and quality of life are mandatory.