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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Cancer Therapies02:49

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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Related Experiment Video

Updated: Apr 15, 2026

Electrochemotherapy of Tumours
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Electrochemotherapy of Tumours

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Chemotherapy for advanced cancers.

Padma Sheila Rajagopal1, Ryan D Nipp2, Kathy J Selvaggi3

  • 1Columbia University College of Physicians and Surgeons, 630 W. 168th St., New York, NY 10032, USA.

Annals of Palliative Medicine
|April 6, 2015
PubMed
Summary
This summary is machine-generated.

For advanced cancers, chemotherapy decisions require careful consideration of benefits and palliative care. Palliative chemotherapy should be reevaluated when it no longer controls disease or improves quality of life (QOL).

Keywords:
Palliative careantineoplastic agentsneoplasms

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Area of Science:

  • Oncology
  • Palliative Care

Background:

  • Chemotherapy decisions in advanced cancers are complex, balancing indications and benefits.
  • Multidimensional cancer treatment should involve oncologists and palliative care specialists.
  • Palliative care should be integrated with chemotherapy when curative intent is lost.

Purpose of the Study:

  • To provide a foundation for discussing treatment in advanced malignancies.
  • To emphasize the role of palliative chemotherapy and its continuous reevaluation.
  • To guide oncologists in weighing chemotherapy's benefits for symptom palliation and quality of life (QOL).

Main Methods:

  • This is a review article.
  • It synthesizes current understanding of palliative chemotherapy in advanced cancers.
  • It aims to inform clinical decision-making.

Main Results:

  • Chemotherapy in advanced cancer often aims to palliate symptoms and improve QOL.
  • Palliative chemotherapy requires ongoing assessment throughout a patient's illness.
  • The role of chemotherapy should be reconsidered if it ceases to control disease or alleviate symptoms.

Conclusions:

  • Palliative chemotherapy can be delivered concurrently with antineoplastic agents when curative intent is absent.
  • Continuous reevaluation of palliative chemotherapy's role is crucial.
  • Discussions regarding treatment for advanced malignancies should incorporate palliative care principles.