Related Experiment Video
Updated: Apr 15, 2026
12:16
Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells
Published on: December 17, 2015
27.2K
Filifactor alocis--a new emerging periodontal pathogen
A Wilson Aruni1, Arunima Mishra1, Yuetan Dou1
1Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, CA 92354, USA.
Microbes and Infection
|April 6, 2015
Summary
Filifactor alocis, a newly identified Gram-positive anaerobic rod, is an emerging pathogen linked to periodontal disease. Its unique molecular characteristics are crucial for understanding its role in disease progression.
Area of Science:
- Microbiology
- Periodontology
- Pathogen Discovery
Background:
- Periodontal disease is a prevalent inflammatory condition affecting the gums and supporting bone structures.
- The role of specific bacterial species in the pathogenesis of periodontal disease is an active area of research.
- Filifactor alocis (F. alocis) has recently been recognized as a potentially significant contributor to periodontal disease.
Purpose of the Study:
- To discuss the unique characteristics of Filifactor alocis.
- To explore molecular variations that may contribute to F. alocis' pathogenicity.
- To highlight F. alocis as an emerging pathogen in periodontal disease.
Main Methods:
- Literature review and analysis of existing data on Filifactor alocis.
- Molecular characterization of F. alocis strains (details not provided in abstract).
- Comparative analysis of F. alocis with other periodontal pathogens.
Main Results:
- Filifactor alocis is a Gram-positive anaerobic rod.
- F. alocis exhibits unique molecular variations.
- These variations are hypothesized to mediate the pathogenic process in periodontal disease.
Conclusions:
- Filifactor alocis is an emerging pathogen with a potential significant role in periodontal disease.
- Understanding the molecular basis of F. alocis pathogenicity is crucial for developing targeted therapies.
- Further research is warranted to fully elucidate the mechanisms by which F. alocis contributes to periodontal disease.
More Related Videos
Related Concept Videos
01:28Development of the Oral Microbiota
44
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
44
01:27The Oral Microbiota
57
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
57
01:26Bacterial Phylum Proteobacteria
1.2K
Proteobacteria, one of the largest and most diverse bacterial phyla, encompasses a wide range of Gram-negative bacteria distinguished by their outer membrane composed of lipopolysaccharides. These microorganisms exhibit various metabolic capabilities, including phototrophy, chemolithotrophy, and heterotrophy, and thrive in diverse environments from soil to aquatic systems and host-associated niches. The phylum is divided into six classes: Alphaproteobacteria, Betaproteobacteria,...
1.2K
01:26Bacterial Phylum Bacteroidota
897
The phylum Bacteroidota includes over 700 species classified into four primary orders: Bacteroidales, Cytophagales, Flavobacteriales, and Sphingobacteriales. These gram-negative, non-sporulating rods exhibit saccharolytic capabilities and can be aerobic or fermentative, encompassing obligate aerobes, facultative aerobes, and obligate anaerobes. Many species display gliding motility, though some are nonmotile or use flagella. The genus Bacteroides is well-studied due to its significant role in...
897
01:26Bacterial Phylum Planctomycetes
553
Planctomycetes are a group of morphologically distinct bacteria predominantly classified into two orders: Planctomycetales and Brocadiales. These gram-negative bacteria exhibit unique features, including division by budding and the presence of stalks or appendages. Their cells are often found in rosette arrangements, and they are notable for possessing an S-layer in their cell envelope, which is relatively uncommon among bacteria. Additionally, Planctomycetes frequently exhibit intracellular...
553
01:30Bacterial Phylum Actinobacteria
890
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
890