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Updated: Apr 15, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
Central retinal artery occlusion and infective endocarditis: rigor does matter
J Piqueras Flores1, G Esquinas Blanco2, M Pinilla Rivas3
1Servicio de Cardiología, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
Central retinal artery occlusion (CRAO) can be a rare symptom of infective endocarditis. Prompt diagnosis of this serious condition requires high clinical suspicion, even without typical fever.
Area of Science:
- Ophthalmology
- Cardiology
- Infectious Diseases
Background:
- Infective endocarditis (IE) is a serious infection of the heart valves.
- Central retinal artery occlusion (CRAO) is a rare but devastating ophthalmological emergency.
Observation:
- A patient presented with acute amaurosis (vision loss) as the sole symptom.
- The patient had a history of mitral regurgitation and positive blood cultures for Streptococcus viridans.
Findings:
- Transesophageal ultrasound revealed native valve infective endocarditis.
- CRAO was the presenting manifestation of IE in this afebrile patient.
Implications:
- This case highlights the diverse presentations of infective endocarditis.
- Ophthalmologists and cardiologists must maintain high clinical suspicion for IE in patients with CRAO, even without fever.
- Systematic evaluation is crucial for identifying serious underlying conditions associated with CRAO.
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