Related Experiment Video
Updated: Apr 15, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
Published on: May 27, 2014
Crystal structure of the tripeptide N-(benzyl-oxycarbon-yl)glycylglycyl-l-norvaline
1Dept. of Physics, Indian Institute of Science, Bangalore 560012, India.
Abstract:
The title tripeptide, C17H23N3O6, contains a nonproteinogenic C-terminal amino acid residue, norvaline, which is an isomer of the amino acid valine. Norvaline, unlike valine, has an unbranched side chain. The mol-ecule has a Gly-Gly segment which adopts an extended conformation. The norvaline residue also adopts an extended backbone conformation while its side chain has a g (+) t conformation. In the crystal lattice, N-H⋯O and O-H⋯O hydrogen bonds stabilize the packing. Mol-ecules translated along the crystallographic a axis associate through an N-H⋯O hydrogen bond. The remaining three hydrogen bonds are between mol-ecules related by a 2 1 screw axis.
More Related Videos
09:31PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase
Published on: September 26, 2020
07:26Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Related Concept Videos
Protein Organization
The primary structure of a protein is its amino acid sequence....
Protein Organization
Protein Folding Quality Check in the RER
Peptide Bonds
Structures of Carboxylic Acid Derivatives
Carboxylic acid derivatives contain an acyl group attached to a heteroatom such as chlorine, oxygen, or nitrogen. The carbonyl carbon and oxygen are both sp2-hybridized with an unhybridized p orbital.
The three sp2 orbitals of the carbonyl carbon form three σ bonds, one each with the carbonyl oxygen, the α carbon, and the heteroatom, whereas the other two sp2 orbitals of the carbonyl oxygen are occupied by the lone pairs. Further, the...
Protein and Protein Structure
A protein's shape is critical to its function. For example, an enzyme...