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Related Experiment Videos

Pathology of tropical appendicitis.

S C Gupta1, A K Gupta, N K Keswani

  • 1Department of Pathology and Surgery, MLN Medical College, Allahabad, India.

Journal of Clinical Pathology
|November 1, 1989
PubMed
Summary

Routine histopathological examination of appendectomy specimens is crucial. This practice can uncover significant, treatable conditions in 5% of cases, including infections and tumors, which might otherwise be missed.

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Area of Science:

  • Pathology
  • Gastroenterology
  • Surgical Pathology

Background:

  • Appendectomies are common surgical procedures.
  • Histopathological examination of appendectomy specimens is standard practice.
  • The diagnostic yield of routine histopathology for appendectomies can vary.

Purpose of the Study:

  • To evaluate the clinical significance of routine histopathological examination of all appendectomy specimens.
  • To determine the frequency of clinically important findings missed by gross examination alone.

Main Methods:

  • Retrospective analysis of 2921 appendectomy specimens performed over 25 years.
  • Review of histopathological reports for all specimens.
  • Categorization of findings into normal, incidental, or clinically significant pathological conditions.

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Main Results:

  • Histopathological examination provided additional information in 5% (153) of cases.
  • Significant findings included tuberculosis (2.3%), parasitic infestations (2.5% - enterobiasis, amoebiasis, ascariasis, taeniasis), mucocele (0.1%), and carcinoid tumors (0.1%).
  • In 95% of cases, histopathology confirmed routine findings without adding new clinical information.

Conclusions:

  • Routine histopathological examination of all appendectomy specimens is recommended.
  • This practice is essential for detecting rare but clinically important and treatable conditions.
  • Pathological evaluation ensures comprehensive patient care and avoids diagnostic omissions.