Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Self-Reporting Supramolecular Coacervates Driven by Liquid-Liquid Phase Separation Enable Systemic Translocation and Photodynamic Bioprotection.

Biomacromolecules·2026
Same author

Physics-Informed Neural Network-Based Elevator Degradation Diagnosis and Early Warning.

Sensors (Basel, Switzerland)·2026
Same author

Water-insoluble components of PM<sub>2.5</sub> are major triggers of pulmonary ferroptosis by inducing mitochondrial damage via Nrf2/Prdx6 pathway.

Ecotoxicology and environmental safety·2026
Same author

A new clade of H9N2 avian influenza virus circulating in Laos.

Emerging microbes & infections·2026
Same author

Association Between Metabolic Clusters and Microbial Age in High-Risk Populations for Diabetes and Their Potential Impact on Cardiovascular Disease Risk: Cross-Sectional Observational Study.

JMIR medical informatics·2026
Same author

Machine learning-integrated network toxicology uncovers glioma targets of DEHP.

Frontiers in toxicology·2026
Same journal

Metal-Organic Framework Monoliths Derived from Emulsion-Templated Foams for Reactive Filtration.

ACS applied materials & interfaces·2026
Same journal

Binary to Quaternary Rare-Earth Phosphates: Compositional Effects on Thermal Properties and CMAS Corrosion Resistance of Environmental Barrier Coatings.

ACS applied materials & interfaces·2026
Same journal

Suture-Free Piezoelectric Band-Aid Membrane for Complex Peripheral Nerve Defects.

ACS applied materials & interfaces·2026
Same journal

Single-Precursor to Dual-Function: A Transformable Metal-Organic Framework Nanoplatform for Photocatalytic H<sub>2</sub> Evolution and CO<sub>2</sub> Reduction.

ACS applied materials & interfaces·2026
Same journal

Surfactant-Templated Synthesis of Mg-Stabilized High-Loading Co Single Atoms in Mesoporous Silica Featuring Robust Co-O Bonds for Efficient Peroxymonosulfate Activation.

ACS applied materials & interfaces·2026
Same journal

Toughening Driven by Interphase Tuning in Bioinspired Nanocomposites: From Structural Engineering to Scalable Fabrication.

ACS applied materials & interfaces·2026
See all related articles

Related Experiment Video

Updated: Apr 15, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

14.2K

Polyisobutylene-Based pH-Responsive Self-Healing Polymeric Gels.

Ujjal Haldar1, Kamal Bauri1, Ren Li2

  • 1†Polymer Research Centre, Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur-741246, Nadia, West Bengal India.

ACS Applied Materials & Interfaces
|April 7, 2015
PubMed
Summary
This summary is machine-generated.

This study presents self-healing polymer gels created using dynamic covalent chemistry. These gels form reversible imine bonds, enabling self-repair without external triggers, showcasing tunable mechanical properties and pH-responsive behavior.

Keywords:
amino acidspolyisobutylenereversible sol−gel transitionself-healingstorage modulus

More Related Videos

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release
08:39

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

9.6K
Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.7K

Related Experiment Videos

Last Updated: Apr 15, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

14.2K
Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release
08:39

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

9.6K
Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.7K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Supramolecular Chemistry

Background:

  • Dynamic covalent chemistry offers pathways to stimuli-responsive and self-healing materials.
  • Polymer gels with tunable mechanical properties are crucial for advanced applications.
  • Self-healing materials reduce waste and extend product lifespans.

Purpose of the Study:

  • To synthesize self-healing gels using dynamic covalent chemistry.
  • To investigate the mechanical properties and self-healing capabilities of the synthesized gels.
  • To explore the influence of pH on the gel's sol-gel transition.

Main Methods:

  • Synthesis of polyisobutylene (PIB) based diblock copolymers with primary amine leucine pendant groups.
  • Cross-linking with PIB-based dialdehyde functionalized cross-linker via imine bond formation.
  • Rheological measurements to assess mechanical properties (storage and loss modulus) and self-healing via step-strain tests.
  • FT-IR spectroscopy for imine bond confirmation and FE-SEM for porosity analysis.
  • pH-triggered sol-gel transitions using hydrochloric acid (HCl) and triethylamine (Et3N).

Main Results:

  • Successful formation of self-healing gels through dynamic imine bond chemistry without external stimuli.
  • Gels exhibited elastic-dominated rheological behavior (G' > G″) with modulus dependent on cross-linking.
  • Demonstrated reversible sol-gel transitions over multiple cycles triggered by pH changes.
  • FT-IR confirmed imine bond formation; FE-SEM revealed poor swelling due to low porosity.

Conclusions:

  • Dynamic covalent chemistry provides an effective route for creating self-healing polymer gels.
  • The synthesized gels possess tunable mechanical properties and reversible pH-responsive behavior.
  • These materials hold potential for applications requiring autonomous repair and controlled phase transitions.