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Related Experiment Video

Updated: Apr 15, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa
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Transcutaneous Electrical Nerve Stimulation Increases Rectal Activity in Children.

Iben Moeller Joensson1, Soren Hagstroem, Charlotte Siggaard

  • 1*Institute of Clinical Medicine, Aarhus University†Department of Pediatrics, Aarhus University Hospital‡Neurogastroenterology Unit, Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.

Journal of Pediatric Gastroenterology and Nutrition
|April 7, 2015
PubMed
Summary

Transcutaneous electrical nerve stimulation (TENS) acutely increases rectal contractions in children with overactive bladder. This effect on rectal motility is temporary and disappears when stimulation stops.

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Area of Science:

  • Pediatric Urology
  • Neurogastroenterology
  • Urodynamics

Background:

  • Neurostimulation is a growing treatment for bladder and bowel dysfunction.
  • The impact of neurostimulation on rectal motility remains unclear.
  • Overactive bladder (OAB) in children often involves complex bladder and bowel issues.

Purpose of the Study:

  • To investigate the acute effects of transcutaneous electrical nerve stimulation (TENS) on rectal motility in pediatric patients with OAB.
  • To determine if TENS influences rectal contractions during urodynamic assessment.

Main Methods:

  • A double-blind, placebo-controlled study involving 20 children with OAB.
  • 48-hour urodynamic monitoring with rectal manometry.
  • Randomization to active TENS or placebo stimulation applied via sacral electrodes.

Main Results:

  • No significant baseline difference in rectal contractions between TENS and placebo groups.
  • Active TENS significantly increased the proportion of time with rectal contractions compared to placebo (51% vs. 32%, P=0.02).
  • Rectal activity returned to baseline levels after TENS was discontinued.

Conclusions:

  • Transcutaneous electrical nerve stimulation (TENS) demonstrates an acute positive effect on rectal motility in children with OAB.
  • The observed increase in rectal contractions is transient and ceases upon removal of stimulation.
  • TENS may be a potential intervention for managing associated rectal dysfunction in pediatric OAB.