Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Lymphatic and Immune System01:23

Introduction to Lymphatic and Immune System

19.8K
Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are born...
19.8K
What is the Immune System?01:38

What is the Immune System?

150.0K
Overview
150.0K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

13.2K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
13.2K
Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

8.4K
The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
8.4K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

2.6K
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
2.6K
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

4.6K
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pig Kidney Xenotransplantation: Immune Insights From a Landmark Human Case.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same author

Generation of Regulatory Dendritic Cells From Living Donor Liver Transplant Perfusates.

Transplantation·2026
Same author

Sustained function and composite immunity of a 61-day pig-to-human decedent thymokidney xenotransplant.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2026
Same author

Donor-derived regulatory dendritic cell infusion and early immunosuppressive drug withdrawal in living-donor liver transplantation: a phase I/IIa trial.

Nature communications·2026
Same author

Donor-recipient mismatch at the <i>SIRPA</i> locus adversely affects kidney allograft outcomes.

Science translational medicine·2025
Same author

Sensitization in Transplantation Assessment of Risk 2025 innate working group: The potential role of innate allorecognition in kidney allograft damage.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2025

Related Experiment Video

Updated: Apr 15, 2026

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses
09:43

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses

Published on: March 8, 2024

2.7K

A brief journey through the immune system.

Karim M Yatim1, Fadi G Lakkis2

  • 1Thomas E. Starzl Transplantation Institute and the Departments of Surgery, Immunology, and Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Clinical Journal of the American Society of Nephrology : CJASN
|April 8, 2015
PubMed
Summary

This review introduces the immune system for nephrologists, explaining its basic functions and relevance to kidney health. Understanding immunology is crucial for diagnosing and treating kidney diseases caused by immune system dysfunctions.

Keywords:
ARFGNimmunologyrenal transplantationtolerance

More Related Videos

Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes
08:14

Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes

Published on: May 8, 2016

28.7K
Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
05:58

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Published on: April 20, 2016

19.9K

Related Experiment Videos

Last Updated: Apr 15, 2026

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses
09:43

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses

Published on: March 8, 2024

2.7K
Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes
08:14

Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes

Published on: May 8, 2016

28.7K
Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
05:58

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Published on: April 20, 2016

19.9K

Area of Science:

  • Immunology
  • Nephrology

Background:

  • The immune system protects the body from pathogens.
  • Dysregulation of the immune system can lead to kidney disease.

Purpose of the Study:

  • To provide an introductory overview of the immune system for nephrologists.
  • To explain the relationship between immune system function and kidney health.

Main Methods:

  • Review of fundamental immunology concepts.
  • Evolutionary perspective on immune system function.
  • Focus on broad concepts rather than specific details.

Main Results:

  • The immune system comprises innate and adaptive divisions.
  • Cellular and tissue components function and are regulated through specific mechanisms.
  • Immune system imperfections can cause renal disease.

Conclusions:

  • A foundational understanding of immunology is essential for nephrologists.
  • The evolutionary basis of the immune system helps explain its role in kidney disease.
  • This review simplifies complex immunology to highlight its clinical relevance in nephrology.