Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Apr 15, 2026

Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.8K

Cellular aggregate capture by fluidic manipulation device highly compatible with micro-well-plates.

Satoshi Konishi1, Yumi Teramachi, Shuhei Shimomura

  • 1Department of Mechanical Engineering, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga, 525-8577, Japan, konishi@se.ritsumei.ac.jp.

Biomedical Microdevices
|April 8, 2015
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Convective flow in coalesced droplets under a temperature difference for uniform distribution of microspheres in vertical contact-separation.

Soft matter·2026
Same author

Force-sensor-integrated soft microfinger for mechanical stimulation and generated force evaluation of zebrafish larvae.

Scientific reports·2026
Same author

Soft microfingers with flexible tactile sensor using liquid metal for in situ evaluation of cellular spheroid stiffness.

Scientific reports·2026
Same author

Microfinger robot with inhaling channels for active sampling and analyzing gaseous and liquid substances toward source localization.

Scientific reports·2026
Same author

Platform design of hybrid microphysiological system integrating in vitro and in silico models for reproducing insulin-regulated glucose metabolism.

Scientific reports·2026
Same author

Effect of prolonged sitting with stair climbing exercise "snacks" on circulating myokines profiles.

European journal of applied physiology·2026

This study introduces a novel capture device for precise cellular aggregate manipulation in micro-wells, overcoming limitations of traditional pipetting methods. The device ensures reliable, high-throughput transport and confirmation of cellular aggregate handling.

Area of Science:

  • Biotechnology
  • Microfluidics
  • Cellular Engineering

Background:

  • Manual manipulation of cellular aggregates using pipettes in micro-wells suffers from low reliability and throughput.
  • Existing methods lack efficient confirmation of task completion for cellular aggregate handling.
  • Compatibility with standard micro-well plates is crucial for practical application.

Purpose of the Study:

  • To propose and design a novel capture device for manipulating and transporting cellular aggregates within micro-wells.
  • To address the limitations of current manual manipulation techniques.
  • To ensure the device is compatible with existing micro-well plate formats.

Main Methods:

  • A new capture device was designed to flow and carry cellular aggregates from the bottom of a micro-well to an integrated trap.

More Related Videos

Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
08:02

Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform

Published on: November 7, 2013

13.5K
Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

28.2K

Related Experiment Videos

Last Updated: Apr 15, 2026

Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.8K
Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
08:02

Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform

Published on: November 7, 2013

13.5K
Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

28.2K
  • A curved surface was engineered at the device's base to create a channel between the device and the micro-well wall.
  • The concept, design, and fabrication of the capture device were detailed, followed by experimental validation.

    • Main Results:

    • The developed capture device successfully manipulates and transports cellular aggregates within micro-wells.
    • Experimental results demonstrate the efficacy of the designed curved surface in forming a functional channel.
    • The device shows promise for reliable and high-throughput cellular aggregate handling.

    Conclusions:

    • The proposed capture device offers a significant improvement over manual pipetting for cellular aggregate manipulation.
    • The design's compatibility with micro-well plates facilitates integration into existing laboratory workflows.
    • Successful experimental validation confirms the device's potential for advancing cellular research and applications.