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[Mesothelioma and familial Mediterranean fever: A relationship?]

S Challita1, A Guerder1, M-C Charpentier2

  • 1Service de pneumologie et soins intensifs respiratoires, groupe hospitalier Cochin Broca Hôtel-Dieu, université Paris Descartes, AP-HP, Paris, France.

Revue Des Maladies Respiratoires
|April 8, 2015
PubMed
Abstract

Insights

This case study highlights a rare instance of pleural mesothelioma in a patient with periodic disease (familial Mediterranean fever). The findings suggest a potential, though unproven, link between recurrent serositis and mesothelioma development in asbestos-unexposed individuals.

Area of Science:

  • Oncology
  • Immunology
  • Genetics

Background:

  • Mesothelioma is often linked to asbestos, but 20% of cases lack this exposure history.
  • Periodic diseases, like familial Mediterranean fever (FMF), involve recurrent serositis, potentially predisposing to mesothelioma.
  • Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent episodes of serositis.
Keywords:
Familial Mediterranean feverFièvre méditerranéenne familialeMaladie périodiqueMesotheliomaMésothéliomePeriodic diseasePleuraPlèvreSerositisSéreuses

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