Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

754
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
754
Microbial Interactions: Parasitism01:22

Microbial Interactions: Parasitism

79
Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...
79
Microbial Interactions: Cooperation01:26

Microbial Interactions: Cooperation

44
Microbial cooperation involves beneficial interactions in which different species work together for individual or mutual advantage. These interactions can profoundly influence ecological dynamics and evolutionary processes, and they are essential to many pathogenic and symbiotic relationships.Nematode–Bacteria CooperationA striking example is the relationship between the Gram-negative bacterium Xenorhabdus nematophila and the parasitic nematode Steinernema carpocapsae. Juvenile nematodes...
44
Microbe-Plant Interactions01:09

Microbe-Plant Interactions

88
Microbe-plant interactions represent a dynamic spectrum of associations shaped by intricate chemical signaling. These interactions can be neutral, beneficial, or detrimental, and profoundly influence plant physiology, growth, and ecosystem function. The plant microbiome, comprising bacteria, fungi, archaea, protists, and viruses, plays a pivotal role in mediating these effects through surface colonization, internal colonization, or systemic symbiosis.Mutualistic associations, particularly with...
88
Microbial Interactions: Mutualism01:25

Microbial Interactions: Mutualism

60
Mutualism is a symbiotic interaction in which all participating organisms benefit. These relationships can be obligate or facultative and are fundamental to ecosystem functions across diverse biological systems.Plant–Fungi MutualismOne well-known example is the association between plant roots and mycorrhizal fungi, such as Rhizophagus species. The fungal hyphae penetrate the root hairs and the epidermis, forming an extensive hyphal network that establishes a symbiotic association. Through...
60
Diversity of Protists II01:27

Diversity of Protists II

2.2K
Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Viral infection drives cell-intrinsic re-localization of the <i>C. elegans</i> immune-repressive STAT transcription factor STA-1.

bioRxiv : the preprint server for biology·2026
Same author

Intestinal and epidermal-specific analysis of ZIP-1 function and expression in <i>Caenorhabditis elegans</i>.

microPublication biology·2026
Same author

Immune regulators PALS-25 and PALS-22 localize to mitochondria and regulate mitochondrial fragmentation in <i>C. elegans</i>.

iScience·2026
Same author

Intersections between proteostasis and immunity: insights from Caenorhabditis elegans.

Disease models & mechanisms·2026
Same author

The functional landscape of the human ubiquitinome.

bioRxiv : the preprint server for biology·2025
Same author

The <i>C. elegans</i> immune switch proteins PALS-25 and PALS-22 localize to mitochondria and regulate fragmentation.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: Apr 15, 2026

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
09:24

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Published on: April 6, 2022

2.9K

Microsporidia-host interactions.

Suzannah C Szumowski1, Emily R Troemel1

  • 1Division of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, United States.

Current Opinion in Microbiology
|April 8, 2015
PubMed
Summary

Microsporidia are pathogens that infect animals, but how hosts respond is unclear. Recent studies reveal microsporidia manipulate host immunity, cell processes, and even insect behavior.

More Related Videos

Author Spotlight: Advanced Enteroid Model for Studying Host-Pathogen Interactions
07:56

Author Spotlight: Advanced Enteroid Model for Studying Host-Pathogen Interactions

Published on: April 5, 2024

2.8K
A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

11.7K

Related Experiment Videos

Last Updated: Apr 15, 2026

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
09:24

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Published on: April 6, 2022

2.9K
Author Spotlight: Advanced Enteroid Model for Studying Host-Pathogen Interactions
07:56

Author Spotlight: Advanced Enteroid Model for Studying Host-Pathogen Interactions

Published on: April 5, 2024

2.8K
A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

11.7K

Area of Science:

  • Microbiology
  • Pathogen-host interactions
  • Animal pathology

Background:

  • Microsporidia are obligate intracellular pathogens infecting diverse animals.
  • Host responses to microsporidia remain poorly understood.
  • Recent research offers new insights into host-pathogen dynamics.

Purpose of the Study:

  • To summarize recent findings on host responses to microsporidia infection.
  • To highlight mechanisms of microsporidia-host interaction.
  • To underscore the impact of microsporidia on host physiology and behavior.

Main Methods:

  • Review of recent transcriptional studies.
  • Analysis of host gene regulation during infection.
  • Investigation of microsporidia's interaction with host cellular pathways.

Main Results:

  • Microsporidia infection alters genes in innate immunity, ubiquitylation, metabolism, and hormonal signaling.
  • Microsporidia utilize host endocytosis for cell exit.
  • Microsporidia interact with host degradation pathways.
  • Infection impacts insect host behavior.

Conclusions:

  • Microsporidia actively manipulate host cellular processes and immune responses.
  • Understanding these interactions is crucial for comprehending microsporidiosis.
  • Further research is needed to fully elucidate microsporidia's impact on animal hosts.