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Updated: Apr 15, 2026

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase
Published on: April 23, 2019
A Sensory 3D Map of the Odor Description Space Derived from a Comparison of Numeric Odor Profile Databases
1Department of Applied Statistics, Universidad Politécnica de Valencia, Camino de Vera s/n edificio 7A, 46022 Valencia, Spain mazarcas@eio.upv.es.
Abstract:
Many authors have proposed different schemes of odor classification, which are useful to aid the complex task of describing smells. However, reaching a consensus on a particular classification seems difficult because our psychophysical space of odor description is a continuum and is not clustered into well-defined categories. An alternative approach is to describe the perceptual space of odors as a low-dimensional coordinate system. This idea was first proposed by Crocker and Henderson in 1927, who suggested using numeric profiles based on 4 dimensions: "fragrant," "acid," "burnt," and "caprylic." In the present work, the odor profiles of 144 aroma chemicals were compared by means of statistical regression with comparable numeric odor profiles obtained from 2 databases, enabling a plausible interpretation of the 4 dimensions. Based on the results and taking into account comparable 2D sensory maps of odor descriptors from the literature, a 3D sensory map (odor cube) has been drawn up to improve understanding of the similarities and dissimilarities of the odor descriptors most frequently used in fragrance chemistry.
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