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Effects of prolonged head-down bed rest on working memory.

Qing Liu1, Renlai Zhou2, Xin Zhao3

  • 1Beijing Key Lab of Applied Experimental Psychology, School of Psychology, Beijing Normal University, Beijing, People's Republic of China ; Research Center of Emotion Regulation, Beijing Normal University, Beijing, People's Republic of China.

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Prolonged head-down bed rest negatively impacts working memory and physiological responses. Key indicators like galvanic skin response and heart rate variability show significant changes, highlighting the effects of simulated microgravity.

Keywords:
galvanic skin responseheart rateheart rate variability

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Area of Science:

  • Space physiology
  • Neuroscience
  • Human physiology

Background:

  • Prolonged bed rest simulates weightlessness, affecting cerebral circulation and brain function.
  • Understanding these effects is crucial for astronaut health and terrestrial applications.

Purpose of the Study:

  • To investigate the impact of 45-day head-down bed rest on working memory.
  • To assess cognitive and physiological responses during simulated microgravity.

Main Methods:

  • 16 healthy males underwent -6° head-down bed rest for 45 days.
  • Working memory assessed using the 2-back task at various time points.
  • Simultaneous recording of cognitive and physiological data (galvanic skin response, heart rate variability).

Main Results:

  • Significant increase in galvanic skin response post-bed rest.
  • Significant decrease in heart rate variability (HF, LF) and reaction time.
  • Positive correlation between working memory reaction time and LF/HF ratio during bed rest.

Conclusions:

  • Head-down bed rest detrimentally affects physiology and working memory.
  • Galvanic skin response and heart rate variability are sensitive indicators of prolonged bed rest effects.