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Canine Babesiosis in China Caused by Babesia gibsoni: A Molecular Approach
Da-Wei Yao1, Jing-Ya Jiang1, Ze-Zhong Yu2
1College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Background:
To provide a point of reference to study the epidemiology and clinical expression of canine babesiosis in China.
Methods:
A total of 30 dogs infected with canine babesiosis were evaluated by mean of clinical history, physical examination, hematological, restriction fragment length polymorphism of PCR products (PCR-RFLP) and sequencing analysis.
Result:
The most prevalent clinical abnormalities were lethargy (100%), anorexia (100%), pale or icteric mucous membranes (80%), fever (70%) and dark urine (70%). Hematology parameters revealed that anemia and thrombocytopenia were the major abnormalities in blood of dogs infected with canine babesia. The results of PCR-RFLP and sequencing analysis indicated that B. gibsoni was the main species responsible for canine babesiosis cases at the time of the study in Nanjing, China.
Conclusions:
The results provide valuable information for better understanding of the epidemiology of canine babesiosis in China.
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