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Updated: Apr 15, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

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Published on: August 30, 2018

Use of computer decision support in an antimicrobial stewardship program (ASP).

R S Evans¹, J A Olson², E Stenehjem³

¹Medical Informatics, Intermountain Healthcare, University of Utah , Salt Lake City, Utah ; Biomedical Informatics, University of Utah, University of Utah , Salt Lake City, Utah.

Applied Clinical Informatics

|April 8, 2015

Summary

This summary is machine-generated.

New applications improved antimicrobial stewardship programs (ASPs) by providing timely patient data, enabling efficient audits and better antimicrobial use. This enhances clinical decision-making and patient care.

Keywords:

ASP Clinical decision support antibiotic resistance antimicrobial stewardship antimicrobial stewardship program computer decision support medical informatics patient specific alerts

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Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

Area of Science:

Healthcare Informatics
Clinical Pharmacy
Infectious Diseases

Background:

Antimicrobial stewardship programs (ASPs) face challenges with electronic systems, leading to manual data searches and workflow interruptions.
Inefficient information access hinders the ability of ASPs to prospectively audit antimicrobial use and provide timely feedback to clinicians.

Purpose of the Study:

To identify information needs and workflow gaps within current electronic applications and reports for ASPs.
To develop and implement new applications to improve the prospective auditing capabilities of ASPs and enhance antimicrobial use.

Main Methods:

A framework was developed to integrate patient data from electronic medical records, data warehouses, and alert files.
New applications were created using input from pharmacists and infectious disease physicians, aligning with CDC/NHSN antibiotic utilization specifications.
Alerts and reports were generated and disseminated via pagers, emails, and the National Healthcare Surveillance Network (NHSN).

Main Results:

Four novel applications were successfully developed and implemented at Intermountain Medical Center (IMC) and Primary Children's Hospital (PCH).
These applications facilitated the use of updated CDC/NHSN antibiotic utilization specifications.
Data from IMC and PCH demonstrated a general decrease in the targeted antimicrobial drug utilization.

Conclusions:

Effective ASPs require substantial amounts of timely and accessible patient information.
The newly developed applications significantly improved the efficiency of antimicrobial use review and patient prioritization.
These advancements enable ASPs to optimize patient care through more effective antimicrobial stewardship.