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Updated: Apr 15, 2026
A Murine Tail Lymphedema Model
Published on: February 10, 2021
Lymphatic mapping in the treatment of chronic seroma: a case series
Michael Singer1, Kristen Aliano1, Steven Stavrides1
1Long Island Plastic Surgical Group, Garden City, NY.
Objective:
Seromas or lymphoceles are common postoperative complications. This series presents 3 patients with lower extremity seromas refractory to treatment that required lymphatic mapping and lymphatic ligation for closure, and in 1 case, diagnosis.
Methods:
Lymphatic mapping procedure consisted of intraoperative injection of subcutaneous tissue with methylene blue distal to the seroma with observation of dye effluence from transected or injured lymphatics draining into area of seroma.
Results:
In 2 patients, methylene blue dye absorption into lymphatic vessels allowed for optimized visual identification of lymphatic leak and contrast against surrounding tissues. In the third patient, where no lymphocele leak was found, the study was diagnostic and helped to find an alternate etiology for the recurrent seroma.
Conclusion:
Lymphatic mapping with methylene blue dye is an effective tool in the evaluation and diagnosis of chronic seroma.
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