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Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
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[Fever with a rash caused by chronic meningococcemia]
Jeroen Christiaan de Jonge1, Klaas Koop, Mente Bousema
1Afd. Kindergeneeskunde: J.C. de Jonge, coassistent kindergeneeskunde; dr. K. Koop, aios kindergeneeskunde; drs. R. Nuboer, kinderarts.
Nederlands Tijdschrift Voor Geneeskunde
|April 9, 2015
Summary
Chronic meningococcemia, a rare form of meningococcal infection, presents with prolonged fever and purpuric lesions. Prompt antibiotic treatment led to symptom resolution in a teen patient.
Area of Science:
- Infectious Diseases
- Bacteriology
- Clinical Medicine
Background:
- Fever with rash is a frequent clinical presentation with diverse etiologies.
- Prompt diagnosis and treatment are crucial for managing febrile illnesses.
Observation:
- A 14-year-old male presented with a two-week history of fever, myalgia, and purpuric skin lesions.
- Blood cultures confirmed an infection with Neisseria meningitidis.
Findings:
- The patient experienced a complete resolution of symptoms following antibiotic therapy.
- This case highlights a rare manifestation of meningococcal infection.
Implications:
- Chronic meningococcemia should be considered in the differential diagnosis of prolonged fever with purpuric rash and joint pain.
- Early identification and management of Neisseria meningitidis are vital to prevent severe outcomes.
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