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Intracerebral hemorrhage at young age: long-term prognosis

R-J Koivunen1, T Tatlisumak1, J Satopää2

  • 1Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.

European Journal of Neurology
|April 9, 2015
PubMed

Insights

Young patients surviving intracerebral hemorrhage (ICH) face significant long-term risks. Male sex and diabetes increase mortality, while age, stroke severity, and intraventricular hemorrhage predict poor functional outcomes.

Area of Science:

  • Neurology
  • Neurosurgery
  • Public Health

Background:

  • Intracerebral hemorrhage (ICH) is a severe neurological event with high mortality and poor long-term outcomes.
  • Outcomes for young patients with ICH remain under-investigated.

Purpose of the Study:

  • To investigate the long-term mortality and functional outcomes of intracerebral hemorrhage in young adults.
  • To identify factors associated with mortality and unfavorable functional outcomes in this demographic.

Main Methods:

  • A retrospective cohort study of ICH patients aged 16-49.
  • Data linkage with a national cause-of-death register and long-term follow-up (9.7 years median) using the modified Rankin Scale (mRS).
  • Multivariate analysis to identify independent predictors of mortality and functional outcome (mRS 2-5).

Main Results:

  • 10-year survival rate was 88.8% among 1-month survivors.
  • Male sex and diabetes were independently associated with increased mortality.
  • 49% of survivors had unfavorable functional outcomes, predicted by increasing age, stroke severity, and intraventricular hemorrhage.

Conclusions:

  • Approximately 10% of young ICH survivors die within 10 years, with male sex and diabetes as risk factors.
  • Half of young ICH survivors experience poor functional recovery, influenced by age, initial stroke severity, and intraventricular hemorrhage.
Abstract

Keywords:
functional outcomeintracerebral hemorrhagemortalityprognosisstroke in young adults

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