Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Perineal cutaneous basal cell carcinomas in patients with familial seronegative coeliac disease: report of three cases.

The British journal of dermatology·2021

Same author

Treatment options for leishmaniasis.

Clinical and experimental dermatology·2021

Same author

Generalized pustular figurate erythema first report in two COVID-19 patients on hydroxychloroquine.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020

Same author

Interdigital syphilis: a rare form of secondary syphilis.

International journal of STD & AIDS·2019

Same author

Prolonged overall survival following metastasectomy in stage IV melanoma.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019

Same author

Declining recommended surgery in primary cutaneous melanoma: an analysis of risk factors and survival.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019

Same journal

Environmental criteria in dermatology research grants.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026

Same journal

Microneedling with adipose MSC exosomes versus monotherapy for androgenetic alopecia.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026

Same journal

Diabetes and melanoma: Impact on prognosis and healthcare costs.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026

Same journal

Differential survival with adjuvant immunotherapy in stage III acral versus non-acral melanoma.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026

Same journal

Estimating the global burden of mental health disorders associated with atopic dermatitis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026

Same journal

Proteomic analysis in hidradenitis suppurativa reveals systemic inflammation in all disease stages.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 15, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

Neonatal leukaemia cutis.

M Z Handler¹, R A Schwartz¹

¹Dermatology, Pediatrics, Preventive Medicine, Community Health, and School of Public Affairs and Administration, Rutgers University New Jersey Medical School, Newark, NJ, USA.

Journal of the European Academy of Dermatology and Venereology : JEADV

|April 9, 2015

Summary

This summary is machine-generated.

Neonatal leukaemia cutis, a rare skin condition in newborns, presents as magenta nodules. Some cases, without specific genetic markers, may resolve spontaneously without chemotherapy, warranting careful monitoring.

More Related Videos

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

Neonatal Pial Surface Electroporation

Neonatal Pial Surface Electroporation

Published on: May 7, 2014

Related Experiment Videos

Last Updated: Apr 15, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

Neonatal Pial Surface Electroporation

Neonatal Pial Surface Electroporation

Published on: May 7, 2014

Area of Science:

Neonatal dermatology
Pediatric oncology
Cutaneous manifestations of malignancy

Background:

Neonatal leukaemia cutis is a rare skin condition in newborns, often a sign of systemic leukaemia, typically myeloblastic.
It can rarely be limited to the skin, termed neonatal aleukaemic leukaemia cutis.
Presents within the first 4 weeks of life with characteristic 'blueberry muffin' magenta nodules.

Purpose of the Study:

To describe the clinical presentation and management considerations for neonatal leukaemia cutis.
To evaluate the potential for spontaneous remission in cases without 11q23 translocation.
To inform treatment decisions balancing chemotherapy risks with observed remission rates.

Main Methods:

Clinical case observation and review.
Differential diagnosis including neonatal infections (rubella, toxoplasmosis) and other neoplasms (neuroblastoma).
Genetic analysis (11q23 translocation) to guide treatment strategy.

Main Results:

Neonatal leukaemia cutis presents as 'blueberry muffin' lesions, typically sparing mucous membranes, palms, and soles.
Spontaneous remission without systemic progression is reported in cases lacking the 11q23 translocation.
Chemotherapy carries significant morbidity, prompting consideration for conservative management.

Conclusions:

Neonatal aleukaemic leukaemia cutis without 11q23 translocation may not require chemotherapy.
Monitoring for spontaneous resolution of skin lesions and systemic leukaemia signs is a viable approach.
This conservative strategy aims to minimize treatment-related morbidity in select cases.