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Updated: Apr 15, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
An unusual coronary vein lesion thrombus with calcification
J C Ford1, K J Ascah2, V M Walley1
1Anatomical Pathology, Department of Laboratory Medicine, University of Ottawa Heart Institute and Ottawa Civic Hospital, Ottawa, Ontario, Canada.
Insights
This study details a patient with chronic renal failure and secondary hyperparathyroidism, complicated by cardiac calcification. Echocardiography revealed calcification of a cardiac thrombus, mimicking mitral annular calcification.
Area of Science:
- Cardiology
- Nephrology
- Pathology
Background:
- Chronic renal failure can lead to secondary hyperparathyroidism.
- Secondary hyperparathyroidism is associated with widespread calcification in various tissues.
- Cardiac involvement in renal disease requires careful diagnostic consideration.
Purpose of the Study:
- To describe a case of cardiac thrombus calcification in a patient with chronic renal failure and secondary hyperparathyroidism.
- To highlight the echocardiographic features of cardiac thrombus calcification.
- To discuss the differential diagnosis between cardiac thrombus calcification and mitral annular calcification.
Main Methods:
- Case report presentation.
- Echocardiographic imaging of cardiac structures.
- Review of clinical and pathological findings.
Main Results:
- A patient with chronic renal failure and secondary hyperparathyroidism presented with complex cardiac calcifications.
- Echocardiography identified calcification within an occlusive thrombus in the great cardiac vein and coronary sinus.
- The echocardiographic appearance of this thrombus calcification was similar to mitral annular calcification.
Conclusions:
- Calcification of cardiac thrombi can occur in the setting of chronic renal failure and secondary hyperparathyroidism.
- Echocardiography is a valuable tool for identifying cardiac calcifications, but differentiation from other calcific lesions is crucial.
- Recognition of this entity is important for accurate diagnosis and management of cardiac complications in renal disease.
Abstract:
In this article, a patient with chronic renal failure and probable secondary hyperparathyroidism is described; calcification of a variety of cardiac and other structures complicated the latter. Calcification of an occlusive thrombus in the great cardiac vein and coronary sinus was identified by echocardiography, although not initially appreciated as such. The echocardiographic similarity of this lesion to mitral annular calcification is discussed.
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