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Myocardial extramedullary hematopoiesis following myocardial infarction

E F Marley1, H Liapis, J L Hess

  • 1From the Lauren V. Ackerman Laboratory of Surgical Pathology, Barnes and St Louis Children's Hospitals, Washington University Medical Center, St Louis, Missouri, USA.

Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology
|April 9, 2015
PubMed

Extramedullary hematopoiesis (EMH) usually accompanies a chronic hematologic disease in adults or prematurity in neonates. We observed a striking case of EMH in the explanted heart of a 13-year-old boy who underwent transplantation after extensive myocardial infarction. The florid myeloid proliferation raised the possibility of a leukemic process. To our knowledge, extensive myocardial EMH subsequent to myocardial infarction has not been previously reported. Possible mechanisms underlying EMH in the myocardium are presented.

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