Oxalate transport by the human small intestine

Oxalate was transported in vitro by intestinal brush border cells from rabbit and human by a non-energy-dependent diffusion mechanism. An oxalate-binding protein that had an approximate molecular weight of 73,000 was identified in the human intestine (ileum), was localized in the cytosol cell fraction, and was affected by calcium and magnesium, which increased the oxalate binding.