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A random plasma glucose method for screening for gestational diabetes.

J R Maheshwari, M V Mataliya

    Journal of Postgraduate Medicine
    |January 1, 1989
    PubMed
    Summary
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    Screening for gestational diabetes using random plasma glucose (RPG) at the first antenatal visit is effective. This method identified more cases of gestational diabetes compared to traditional screening criteria.

    Area of Science:

    • Obstetrics and Gynecology
    • Endocrinology
    • Clinical Diagnostics

    Background:

    • Pregnancy commonly causes a low renal glucose threshold, making glycosuria unreliable for diagnosing gestational diabetes.
    • Traditional screening methods for gestational diabetes may not be sufficiently sensitive.

    Purpose of the Study:

    • To evaluate the effectiveness of random plasma glucose (RPG) screening for gestational diabetes at the initial antenatal visit.
    • To compare the diagnostic yield of RPG screening against conventional criteria.

    Main Methods:

    • A screening program utilizing RPG was implemented for 12,623 pregnant patients at their first antenatal visit.
    • Patients with RPG levels exceeding 100 mg% were advised to undergo an oral glucose tolerance test.
    • The gestational diabetes pick-up rate was correlated with RPG levels.

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    Main Results:

    • Out of 12,623 patients, 1371 had an RPG > 100 mg%.
    • Thirty-six cases of gestational diabetes were diagnosed.
    • The pick-up rate for gestational diabetes was significantly higher with RPG screening compared to conventional methods.

    Conclusions:

    • Random plasma glucose screening at the first antenatal visit is a more effective method for detecting gestational diabetes.
    • This approach offers improved diagnostic sensitivity over traditional screening criteria.