Acute venous sinus thrombosis after chickenpox infection
The Journal of the Association of Physicians of India
|April 11, 2015
Summary
Varicella zoster virus infection can rarely lead to cerebral venous thrombosis (CVT), a serious neurological complication. This case highlights the importance of considering CVT in adults presenting with neurological deficits after chickenpox.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Medicine
Background:
- Chickenpox, caused by the Varicella zoster virus, is typically a childhood illness.
- Adults can experience severe systemic and neurological complications from chickenpox.
- Cerebral venous thrombosis (CVT) is a critical condition requiring timely treatment.
Observation:
- A 30-year-old immunocompetent male developed chickenpox.
- He presented with acute neurological deficits one week after the onset of skin lesions.
- MR venography confirmed left transverse and sigmoid sinus thrombosis.
Findings:
- Varicella zoster virus infection is an uncommon cause of venous sinus thrombosis.
- Cerebral venous thrombosis is a rare complication of primary Varicella zoster virus infection.
- The case involved an immunocompetent adult male.
Implications:
- Varicella infection may induce a hypercoagulable state.
- Direct viral invasion of the venous endothelium could lead to thrombosis.
- Early recognition and management of post-varicella CVT are crucial for patient outcomes.
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