Related Experiment Videos
[Pulmonary function in normal Japanese children 6 to 16 years of age]
Insights
New pulmonary function prediction equations are needed for Japanese children. Current equations, based on data over 30 years old, overestimate lung function due to improved child growth.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
- Growth and Development
Context:
- Pulmonary function testing is crucial for assessing respiratory health in children.
- Existing prediction equations for Japanese children are outdated, potentially leading to misinterpretation of results.
- Secular trends in growth indicate potential changes in lung volumes.
Purpose:
- To establish updated normative values for pulmonary function in healthy Japanese children.
- To compare new regression equations with previously established ones.
- To highlight the need for current reference standards in pediatric respiratory assessments.
Summary:
- Pulmonary function was measured in 182 healthy Japanese children aged 6-16 years in Tokyo.
- Multiple regression equations were derived and compared to older equations (Kanagami 1958, Ishida 1955).
- New equations yielded predicted values 10-25% higher, attributed to improved child growth, necessitating updated norms.
Impact:
- Provides current, accurate reference ranges for pulmonary function in Japanese children.
- Facilitates more precise diagnosis and monitoring of respiratory conditions in this population.
- Highlights the importance of periodic re-evaluation of predictive equations due to secular growth changes.
Abstract:
We measured pulmonary function on 182 healthy Japanese children 6 to 16 years of age living in the Tokyo area. Static lung volumes, RV/TLC (%), FRC/TLC (%), FVC, FEV1, FEV1/FVC (%), MMFR, MVV, f, VE and VO2 were measured. Multiple regression equations were obtained and the results were compared with those derived from the other equations (Kanagami (1958), Ishida (1955]. The predicted values were about 10 approximately 25% higher with our equations than those obtained from the other equations which were made more than 30 years ago. These differences were attributed to the recent improvement in growth of the Japanese children. For this reason we think it is better now to adopt new equations for the prediction of normal values in Japanese children.