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Updated: Apr 15, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Excess anticoagulation as a cause of small-bowel obstruction: a report of two cases
Henrietta Creasy1, Luke Meleagros2
1North Middlesex University Hospital NHS Trust, London, UK henriettacreasy@gmail.com.
Abstract:
Spontaneous intramural haemorrhage is a rare cause of small-bowel obstruction, occurring most commonly in those who are anticoagulated. We describe two cases that presented with a history and imaging suggestive of small-bowel obstruction; both had International Normalized Ratios of above 10 on admission. The first case, a 62-year-old lady on warfarin for atrial fibrillation, was managed conservatively with good effect. In contrast, the second case, a 57-year-old gentleman on warfarin for his metallic aortic valve, underwent diagnostic laparotomy that revealed a 30-cm segment of proximal jejunum with spontaneous intramural haemorrhage. In this study, we emphasize the merit of conservative management for this rare cause of small-bowel obstruction.
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