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Published on: May 21, 2015
[Detection of gingipain K in the gingival crevicular fluid of orthodontic patients]
Gang-Ling Yang1, Wei-Zhe Li, Zhi-Qiang Han
1Department of Stomatology, Binzhou People's Hospital. Binzhou 256603,China.E-mail:826964972@qq.com.
Purpose:
To explore the correlation between gingipain K (Kgp) and inflammatory reaction of gum in the process of orthodontic treatment, and analyse the role of Kgp in the development of gingivitis during orthodontic treatment.
Methods:
Totally 45 orthodontic healthy teenagers were randomly chosen for the study. The subgingival plaques were collected simultaneously before orthodontic treatment and 3 months after treatment. 16S rDNA PCR technique was used to detect Porphyromonas gingivalis (P.g) and Kgp. SPSS17.0 software package was used for statistical analysis.
Results:
The detection rate of Kgp was 35.71% before orthodontic treatment and 67.86% after treatment. Positive correlation (P<0.05) was observed between Kgp and gingival inflammation.
Conclusions:
Fixed orthodontic appliances cause plaque accumulation, accordingly slight gingiva inflammation and the increament of P.gingivalis in the early stage.
