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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Nephrogenic Systemic Fibrosis on Mammography.

James Choi1, Richard Ha1, Ralph Wynn1

  • 1Department of Radiology, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY.

Current Problems in Diagnostic Radiology
|April 11, 2015
PubMed
Summary

Nephrogenic systemic fibrosis (NSF) is a serious disorder linked to gadolinium contrast agents. This study examines the rare presentation of NSF on mammography, highlighting its appearance in breast tissue.

Area of Science:

  • Radiology
  • Dermatology
  • Nephrology

Background:

  • Nephrogenic systemic fibrosis (NSF), previously nephrogenic fibrosing dermopathy, is a debilitating condition.

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  • NSF is strongly associated with gadolinium-based contrast agents used in MRI.
  • While truncal skin involvement is common, NSF's manifestation on mammography is rarely documented.