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Pharmaceutical approval update.
P & T : a Peer-Reviewed Journal for Formulary Management
|April 11, 2015
Summary
This summary covers four new drug approvals: Palbociclib for breast cancer, secukinumab for psoriasis, Bexsero vaccine for meningitis prevention, and lenvatinib for thyroid cancer.
Area of Science:
- Oncology
- Immunology
- Vaccinology
Background:
- Palbociclib (Ibrance) is a targeted therapy for advanced breast cancer.
- Secukinumab (Cosentyx) is an interleukin-17A inhibitor for plaque psoriasis.
- Meningococcal group B vaccine (Bexsero) offers protection against a common cause of meningitis.
- Lenvatinib (Lenvima) is approved for treating differentiated thyroid cancer.
Purpose of the Study:
- To announce the approval of Palbociclib for breast cancer treatment.
- To report on the efficacy of secukinumab in managing plaque psoriasis.
- To highlight the availability of the Bexsero vaccine for meningitis prevention.
- To detail the use of lenvatinib in differentiated thyroid cancer therapy.
Main Methods:
- Clinical trials evaluated Palbociclib's efficacy in breast cancer patients.
- Studies assessed secukinumab's effectiveness and safety in plaque psoriasis.
- Clinical data supported the use of Bexsero against meningococcal group B infections.
- Research demonstrated lenvatinib's role in treating differentiated thyroid cancer.
Main Results:
- Palbociclib showed significant benefits in breast cancer treatment.
- Secukinumab provided substantial improvement for plaque psoriasis patients.
- Bexsero proved effective in preventing meningitis caused by meningococcal group B.
- Lenvatinib demonstrated positive outcomes in differentiated thyroid cancer.
Conclusions:
- Palbociclib is a valuable new option for breast cancer.
- Secukinumab offers a new therapeutic avenue for psoriasis.
- Bexsero enhances meningitis prevention strategies.
- Lenvatinib expands treatment options for thyroid cancer.
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