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Updated: Apr 15, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Review of Giant cell arteritis
Joseph G Chacko1, J Anthony Chacko2, Michael W Salter1
1Jones Eye Institute, Department of Ophthalmology, University of Arkansas for Medical Sciences, 4301 W. Markham, #523, Little Rock, AR 72205, USA.
Abstract:
Giant-cell arteritis (GCA) is a systemic autoimmune disease affecting primarily the elderly. Giant cell arteritis can cause sudden and potentially bilateral sequential vision loss in the elderly. Therefore, it is considered a medical emergency in ophthalmology and a significant cause of morbidity in an increasingly aging population. Ophthalmologists need to be able to recognize the classic symptoms and signs of this disease, and then be able to work-up and treat these patients in an efficient manner. An in-depth review of GCA from the literature as well as personal clinical experience follows.
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