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Updated: Apr 15, 2026
05:01
A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
Published on: October 17, 2017
7.6K
Intracranial pressure and skull remodeling
Timothy J McCulley1, W Jordan Piluek1, Jessica Chang1
1The Wilmer Eye Institute, Johns Hopkins University School of Medicine, United States.
Summary
Chronic intracranial hypotension can cause significant bony changes, including enophthalmos and ocular surface disease. Early recognition through radiographic assessment is crucial for timely diagnosis and treatment.
Area of Science:
- Ophthalmology
- Neurosurgery
- Orthopedics
Background:
- Intracranial pressure (ICP) significantly influences bone remodeling.
- Alterations in ICP, both hypertension and hypotension, lead to distinct bony changes.
- Understanding these changes is vital for ophthalmologists managing related patient conditions.
Purpose of the Study:
- To review bony changes associated with altered intracranial pressure (ICP).
- To highlight the ophthalmic implications of these bony changes.
- To emphasize the importance of recognizing bony changes in chronic intracranial hypotension.
Main Methods:
- Review of literature on bone remodeling and ICP.
- Discussion of bony changes in chronic intracranial hypotension and hypertension.
- Focus on radiographic assessment for early identification.
Main Results:
- Chronic intracranial hypotension can cause skull remodeling leading to enophthalmos.
- Ocular surface disease, abnormal ocular motility, and optic atrophy are associated findings.
- Radiographic assessment can identify patients with abnormal ICP before severe clinical deterioration.
Conclusions:
- Bony changes due to altered ICP have significant ophthalmic implications.
- Early identification of intracranial hypotension through bony changes is critical.
- Prompt diagnosis and treatment can prevent advanced clinical deterioration and disfigurement.
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