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Duration analysis for coronary artery disease patients with chronic chest pain: an output from saudi arabia

Mehwish Hussain1, Nazeer Khan2, Mudassir Uddin3

  • 1Department of Statistics, University of Karachi, Karachi, Pakistan ; Department of Research, Dow University of Health Sciences, Karachi, Pakistan.

Journal of Cardiovascular and Thoracic Research
|April 11, 2015
PubMed

Insights

The average duration from chronic chest pain to a coronary artery disease (CAD) diagnosis is 5 years. Advancing age, female gender, lack of exercise, and low HDL cholesterol increase CAD risk in patients with chest pain.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Coronary artery disease (CAD) remains a significant global health concern.
  • Chest pain is a key symptom, with acute episodes linked to CAD risk.
  • The time lag between chronic chest pain onset and CAD diagnosis is not well-established.

Purpose of the Study:

  • To determine the average duration from chronic chest pain to CAD diagnosis.
  • To evaluate the influence of various risk factors on this time duration.

Main Methods:

  • A community-based study involving 17,232 Saudi adults.
  • Data collection included patient history of chest pain onset and risk factors.
  • Kaplan-Meier curves and Cox regression models were used for analysis.

Main Results:

  • 24% of participants experienced chest pain, with 21% diagnosed with CAD.
  • The mean duration from chest pain to CAD diagnosis was 5 years.
  • Advancing age, female gender, lack of exercise, and reduced high-density lipoprotein (HDL) were significant predictors of a longer duration.

Conclusions:

  • The established average duration from chest pain to CAD diagnosis is 5 years.
  • Age, gender, exercise habits, and HDL levels are critical factors influencing CAD progression in patients with chest pain.
Abstract

Keywords:
Chronic Chest PainCoronary Artery DiseaseDiagnosisDuration AnalysisPredictors

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