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Abstract:
Life-time microscopy showed possible direct effects of obsidan on lymph vessels and flow in the experiment. With local application of the drug there was a short-term constriction, higher frequencies and lower amplitudes of lymphangionic pulsation; during its intramuscular injection, sustained dilator effects, two-phase shifts in the frequency and limitation of pulse amplitude were seen. With the two routes of obsidan administration heterogenous, unpersistent changes in the linear velocity of lymph flow were observed.