Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac function in endocrine diseases: I. Acromegaly.

R Griebenow1, L Krämer, U Frangenberg

  • 1Medizinische Universitätsklinik II, Universität Köln.

Klinische Wochenschrift
|November 17, 1989
PubMed
Summary

Acromegaly patients show increased cardiac contractility and relaxation, with some developing left ventricular hypertrophy and hypertension. Echocardiography reveals distinct cardiac changes in acromegaly.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of Malignancies in Patients With Primary Aldosteronism.

The Journal of clinical endocrinology and metabolism·2016
Same author

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.

Journal of internal medicine·2013
Same author

Comparison of two mitotane starting dose regimens in patients with advanced adrenocortical carcinoma.

The Journal of clinical endocrinology and metabolism·2013
Same author

Mitotane levels predict the outcome of patients with adrenocortical carcinoma treated adjuvantly following radical resection.

European journal of endocrinology·2013
Same author

Survivin in adrenocortical tumors - pathophysiological implications and therapeutic potential.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2012
Same author

[A 47-year-old patient with paroxysmal arterial hypertension and gastric tumors].

Der Internist·2012

Area of Science:

  • Cardiology
  • Endocrinology
  • Medical Imaging

Background:

  • Acromegaly, a condition caused by excess growth hormone, can lead to significant cardiovascular complications.
  • Understanding cardiac function in acromegaly is crucial for patient management and prognosis.

Purpose of the Study:

  • To characterize cardiac function and anatomy in patients with acromegaly using echocardiography.
  • To compare echocardiographic findings in acromegalic patients with a healthy control group.

Main Methods:

  • Double M-mode echocardiography was performed on 14 acromegaly patients and 24 healthy volunteers.
  • Key cardiac parameters including left ventricular diameter, wall thickening velocity, and relaxation period were measured and compared.

Main Results:

Related Experiment Videos

  • Acromegaly patients exhibited a greater mean left ventricular diameter at end-diastole compared to controls.
  • Significantly increased systolic wall thickening velocity and diameter change indicated enhanced contractility and relaxation in acromegalics.
  • Left ventricular hypertrophy was observed in 3 patients, with 3 patients total diagnosed with hypertension.

Conclusions:

  • Acromegaly is associated with distinct echocardiographic findings, including increased left ventricular diameter and enhanced myocardial contractility and relaxation.
  • A subset of acromegaly patients develop left ventricular hypertrophy and hypertension, highlighting the need for cardiac monitoring.