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Updated: Apr 15, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
AVIA v2.0: annotation, visualization and impact analysis of genomic variants and genes
Hue Vuong1, Anney Che1, Sarangan Ravichandran1
1Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Unlabelled:
As sequencing becomes cheaper and more widely available, there is a greater need to quickly and effectively analyze large-scale genomic data. While the functionality of AVIA v1.0, whose implementation was based on ANNOVAR, was comparable with other annotation web servers, AVIA v2.0 represents an enhanced web-based server that extends genomic annotations to cell-specific transcripts and protein-level functional annotations. With AVIA's improved interface, users can better visualize their data, perform comprehensive searches and categorize both coding and non-coding variants.
Availability And Implementation:
AVIA is freely available through the web at http://avia.abcc.ncifcrf.gov.
Contact:
Hue.Vuong@fnlcr.nih.gov
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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