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Carrier presentation: a possible strategy for selective in vivo amplification of specific T cells

H M Saxena1, R A Robins, R W Baldwin

  • 1Cancer Research Campaign Laboratories, University Park, Nottingham, U.K.

Medical Hypotheses
|August 1, 1989
PubMed

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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...