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Related Concept Videos

Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
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Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
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Updated: Apr 15, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Petroclival meningiomas.

Jacob B Hunter1, Kyle D Weaver2, Reid C Thompson2

  • 1Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, 7209 Medical Center East South Tower, 21st Avenue South, Nashville, TN 37232, USA.

Otolaryngologic Clinics of North America
|April 13, 2015
PubMed
Summary
This summary is machine-generated.

Petroclival meningiomas, tumors affecting cranial nerves, are often diagnosed in middle-aged women. Current treatment emphasizes subtotal resection and radiotherapy for better outcomes.

Keywords:
ApproachesComplicationsMeningiomaOutcomesPetroclivalSkull base

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Area of Science:

  • Neurosurgery and Oncology
  • Cranial Nerve and Skull Base Tumors

Background:

  • Petroclival meningiomas are tumors arising from the skull base, frequently impacting cranial nerves.
  • These tumors predominantly affect women around 50 years old, presenting with symptoms like headaches and gait disturbances.

Purpose of the Study:

  • To provide a comprehensive review of petroclival meningiomas.
  • To discuss current understanding and management strategies for these challenging tumors.

Main Methods:

  • Systematic literature review of petroclival meningiomas.
  • Analysis of definitions, genetics, clinical presentation, imaging, natural history, and treatment modalities.

Main Results:

  • Common symptoms include headaches, gait disturbances, and cranial neuropathies.
  • Surgical resection followed by radiotherapy is the current trend, with subtotal resection favored.

Conclusions:

  • Petroclival meningiomas require multidisciplinary management.
  • Subtotal resection combined with postoperative radiotherapy represents a key treatment strategy.