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Updated: Apr 15, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
Published on: June 10, 2013
How does early cognitive behavioural therapy reduce postpartum depression?
Abstract:
Postpartum depression (PPD) is a frequent mood disorder. Early identification of mothers at risk is crucial to successful prevention. Cognitive Behavioural Therapy (CBT) is an effective preventing therapy. Objectives of this study are to identify mothers at risk for PPD using the Edinburgh Postnatal Depression Scale (EPDS) and evaluate the efficacy of CBT for the prevention of PPD in these mothers. Women were recruited during their second postpartum day. Two groups were selected: mothers with high risk (EPDS score ≥ 10) and mothers with low risk (EPDS score < 10) of PPD. The first group underwent CBT. Follow up was carried out at 40 days, three, six, and 12 months after childbirth. APGAR score, neonatal hospitalization, delayed breastfeeding, and cesarean section were significant obstetric risk factors. Mothers at high risk of PPD presented a statistically valid improvement of EPDS score. Mothers with low risk of PPD did not have CBT and showed a higher EPDS score than mother at high risk at 12 months. PPD prevention is possible through early identification of mothers at risk and early cognitive behavioural therapy.
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