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Updated: Apr 15, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Clinical case of using manual thrombus aspiration during percutaneous coronary intervention in a patient with
Insights
This case study highlights a patient with ST-segment elevation acute coronary syndrome, likely caused by a thromboembolic event rather than coronary artery disease. Effective intervention involved thrombus aspiration, revealing no significant stenoses.
Area of Science:
- Cardiology
- Interventional Cardiology
- Thrombosis
Background:
- ST-segment elevation acute coronary syndrome (STEMI) requires prompt reperfusion therapy.
- Thromboembolic events can mimic or cause myocardial infarction.
- Persistent atrial fibrillation increases the risk of embolic stroke and systemic embolism.
Observation:
- A patient presented with STEMI despite ineffective prehospital thrombolysis.
- Percutaneous coronary intervention with thrombus aspiration was performed 3.5 hours after symptom onset.
- Angiography revealed no significant coronary artery stenoses after thrombus removal.
Findings:
- The patient had a history of persistent atrial fibrillation and transient ischemic attacks.
- The absence of coronary stenosis post-intervention suggests a non-atherosclerotic, likely thromboembolic, origin of the myocardial infarction.
- Successful thrombus aspiration was achieved, improving the angiographic appearance.
Implications:
- This case underscores the importance of considering thromboembolic causes in myocardial infarction, especially in patients with atrial fibrillation.
- Thrombus aspiration can be a crucial intervention when coronary artery stenosis is not the primary pathology.
- Further investigation into the embolic source is warranted for long-term management.
Abstract:
The paper describes a patient admitted to the Emergency Cardiology Department, A.L. Myasnikov Institute of Clinical Cardiology, for diagnosed ST-segment elevation acute coronary syndrome. At the prehospital stage, the patient received ineffective thrombolytic therapy; percutaneous coronary intervention was made at the Department of X-ray Endovascular Diagnostic and Treatment Methods of the Institute 3.5 hours after disease onset. Repeated thrombus aspirations from the infarction-related artery were carried out, which could have a good angiographic pattern. His medical record shows that the patient has been suffering from persistent atrial fibrillation for a long time. There is also evidence for transient ischemic attacks in 2010 and 2011. The fact that there are no coronary artery stenoses after thrombus removal could suspect the thromboembolic genesis of myocardial infarction.
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