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Quantitative Analysis of Protein Expression to Study Lineage Specification in Mouse Preimplantation Embryos
Published on: February 22, 2016
Evolution of germline segregation processes in animal development
1Asamushi Research Center for Marine Biology, Graduate School of Life Science, Tohoku University, 9 Sakamoto, Asamushi, Aomori, 039-3501, Japan.
Abstract:
Germline segregation is a complex process by which germline cells are separated from somatic tissues during development. Recent animal studies on germline segregation allow for comparisons of the mechanisms used by different species and to propose evolutionary scenarios underlying the diversification of these processes. In this review, several proposed models of germline segregation are presented, and in addition, recent findings from the increasing number of studies are discussed, particularly concerning the need to reconsider these models based on available data.
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