Related Experiment Video
Updated: Apr 15, 2026
RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Identification of human papillomavirus in pterygium
Shirin Hamed-Azzam1, Natalia Edison2, Daniel Briscoe1
1Department of Ophthalmology, Emek Medical Center, Afula, Israel.
Purpose:
The purpose of this study was to evaluate the involvement of human papillomavirus in the pathogenesis of primary and recurrent pterygium in northern Israel.
Methods:
A retrospective study examined 100 randomly chosen pterygium specimens with solar elastosis, from 100 patients who underwent pterygium surgery during 2012-2013 at the Emek Medical Center. All the specimens were analysed for evidence of human papillomavirus infection by immunohistochemistry.
Results:
Human papillomavirus was not detected in any of the 100 pterygia samples by immunohistochemistry. These used samples were taken from 100 patients with mean age of 51.5 years and a primary: recurrent ratio of 8.09:1.
Conclusion:
We conclude from our study that human papillomavirus infection does not appear to be an important pathogenic factor of pterygium in Israel.
