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Adiposity and Insulin Resistance in Children from a Rural Community in Mexico
Lourdes Barbosa-Cortes1, Miguel Angel Villasis-Keever2, Martha Del Prado-Manriquez3
1Unidad de Investigación Médica en Nutrición, México, D.F., México.
Insights
This study found low overweight/obesity rates in rural Mexican children, but identified risks for increased body fat and insulin resistance. Early life growth velocity impacts insulin resistance in this population.
Area of Science:
- Pediatric Endocrinology
- Nutritional Science
- Public Health
Background:
- Limited data exists on overweight, obesity, body composition, and insulin resistance in rural children.
- Characterizing these health indicators is crucial for understanding pediatric health in underserved communities.
Purpose of the Study:
- To assess adiposity and insulin resistance (homeostasis model assessment of insulin resistance - HOMA-IR) in rural Mexican school-aged children.
- To identify factors associated with fat mass and HOMA-IR in this population.
Main Methods:
- Studied 41 school-aged children (9.9 ± 2.5 years) from a Mexican rural community.
- Assessed nutritional status from infancy, anthropometry, energy intake, physical activity, body composition, and biochemical markers.
Main Results:
- Prevalence of overweight/obesity was 7.3%; mean energy intake was below recommendations.
- Females had higher fat mass percentage than males (p = 0.006).
- Early life growth velocity correlated with HOMA-IR; female gender was linked to higher fat mass.
Conclusions:
- Rural Mexican children exhibit low overweight/obesity frequency but face risks for adiposity and insulin resistance.
- Growth velocity in early life is a significant factor associated with insulin resistance in this cohort.
Background And Aims:
The study of the incidence of overweight and obesity as well as body composition and insulin resistance in children from rural communities is scarce. The aims of the study were a) to characterize the adiposity and homeostasis model assessment of insulin resistance (HOMA-IR) in school-age children from a rural community and b) to determine factors associated with fat mass and HOMA-IR in this population.
Methods:
A total of 41 school-aged children (15 males and 26 females; 9.9 ± 2.5 years old) from a Mexican rural community was studied. Trained observers had previously assessed the children's nutritional status during the first 6 months of life. Anthropometry, energy intake, physical activity, body composition and biochemical parameters were measured.
Results:
The overall prevalence of overweight/obesity was 7.3%. The mean energy intake of children was below international recommendations (1,235 ± 400 kcal/day). A higher percentage of fat mass was observed in females (20.3 ± 8.5) than in males (14.1 ± 5.1) (p = 0.006). There were seven children with IR, but we did not observe a correlation between HOMA and BMI percentiles (Pearson's r = 0.09, p = 0.57). In a regression model, gender (females) was the primary factor associated with the percentage of fat mass. The growth velocity during the first 6 months of life was associated with HOMA-IR.
Conclusions:
There is a low frequency of overweight and obesity in children from rural communities in Mexico. However, these children appear to have increased risk of adiposity and insulin resistance.
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