Related Experiment Video

Updated: Apr 15, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

11.7K

Quantifying the Burden of Revision Total Joint Arthroplasty for Periprosthetic Infection

Atul F Kamath1, Kevin L Ong2, Edmund Lau3

  • 1Department of Orthopaedic Surgery, Pennsylvania Hospital, Philadelphia, Pennsylvania.

The Journal of Arthroplasty
|April 14, 2015
PubMed

Insights

Periprosthetic joint infection (PJI) significantly impacts healthcare, driving longer hospital stays and higher costs for revision hip and knee replacements. Understanding PJI

Area of Science:

  • Orthopedic Surgery
  • Infectious Disease
  • Health Services Research

Background:

  • Periprosthetic joint infection (PJI) poses significant clinical and economic challenges.
  • Revision arthroplasty is a common treatment for PJI, but associated resource utilization is not fully characterized.

Purpose of the Study:

  • To evaluate patient and procedure characteristics and resource utilization for revision arthroplasty due to PJI.
  • To compare these factors between revision total hip arthroplasty (RTHA) and revision total knee arthroplasty (RTKA) for PJI.

Main Methods:

  • Analysis of the Nationwide Inpatient Sample (Q4 2005-2010).
  • Inclusion of 235,857 RTHA and 301,718 RTKA procedures.
  • Examination of indications, severity of illness (SOI), length of stay (LOS), and costs.

Main Results:

  • PJI was the leading indication for RTKA and third for RTHA.
  • PJI cases exhibited higher SOI (major for RTHA, moderate for RTKA) and longer LOS.
  • Costs for PJI revision arthroplasty were second only to periprosthetic fracture.

Conclusions:

  • Significant epidemiologic differences exist in PJI management for RTHA versus RTKA.
  • PJI represents a major driver of resource utilization in revision joint arthroplasty.
  • Further research into targeted interventions for PJI in revision arthroplasty is warranted.
Keywords:
epidemiologyinfectionrevision arthroplastytotal hip arthroplasty (replacement)total knee arthroplasty

More Related Videos

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

1.4K
A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials06:18

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

2.0K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.7K
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
347
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
5.0K
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
605
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
739
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
597