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Aspergillus infection in urinary tract post-ureteric stenting
1Department of Microbiology, Narayana Health Multispeciality Hospital, Ahmedabad - 382 424, Gujarat, India.
Abstract:
Fungal infections of the urinary tract are usually encountered following prolonged antibiotic use, instrumentation and indwelling urinary catheters. These type of infections are mostly seen in immuno-compromised patients. Candida is the most common among the fungal infections of urinary tract followed by Aspergillus infection. Here is a case report of a 26 year old diabetic female who presented with abdominal pain, fever, nausea and vomiting. She had undergone double-J stenting 15-20 days back. The cause of the symptoms was not detected till the patient underwent C.T Scan-KUB with excretory urography which showed the displaced D-J stent. Then on performing replacement of D-J stent, cystoscopy was done and the tissue sample was sent for microbiological and histopathological examination. On Microbiological examination, Aspergillus flavus was isolated from the tissue, which was culprit behind the disease. Patient was then treated with anti-fungal drugs, following which she gradually improved.
Insights
A rare case of Aspergillus flavus urinary tract infection was identified in a young diabetic woman with a displaced double-J stent. Prompt diagnosis and antifungal treatment led to her recovery.
Area of Science:
- Urology
- Mycology
- Infectious Diseases
Background:
- Urinary tract fungal infections (UTIs) often occur after antibiotic use, instrumentation, or indwelling catheters, particularly in immunocompromised individuals.
- Candida species are the most common cause of fungal UTIs, followed by Aspergillus species.
Observation:
- A 26-year-old diabetic female presented with abdominal pain, fever, nausea, and vomiting following double-J stent placement.
- Computed Tomography (CT) scan revealed a displaced double-J stent, which was suspected as the cause of her symptoms.
Findings:
- Microbiological examination of tissue obtained during stent replacement and cystoscopy isolated Aspergillus flavus as the causative agent.
- Histopathological examination confirmed the fungal infection.
Implications:
- This case highlights Aspergillus flavus as a potential pathogen in complicated urinary tract infections, especially in patients with indwelling devices and underlying conditions like diabetes.
- Early diagnosis through advanced imaging and microbiological analysis is crucial for effective management with antifungal therapy.
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