Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hypercalcemia in sarcoidosis].

J A Janssen, H A Pols, M G Baggen

    Nederlands Tijdschrift Voor Geneeskunde
    |December 2, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites.

    Arthritis and rheumatism·2005
    Same author

    Estrogen receptor alpha gene polymorphisms and bone mineral density in healthy children and young adults.

    Calcified tissue international·2004
    Same author

    Prevalence and causes of visual field loss in the elderly and associations with impairment in daily functioning: the Rotterdam Study.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2001
    Same author

    Systemic ghrelin levels in subjects with growth hormone deficiency are not modified by one year of growth hormone replacement therapy.

    European journal of endocrinology·2001
    Same author

    Acute effect of pegvisomant on cardiovascular risk markers in healthy men: implications for the pathogenesis of atherosclerosis in GH deficiency.

    The Journal of clinical endocrinology and metabolism·2001
    Same author

    Vitamin D control of osteoblast function and bone extracellular matrix mineralization.

    Critical reviews in eukaryotic gene expression·2001

    Sarcoidosis can present with hypercalcemia and kidney issues due to elevated vitamin D. Prednisone treatment improved these sarcoidosis symptoms, confirming the diagnosis.

    Area of Science:

    • Nephrology
    • Endocrinology
    • Immunology

    Background:

    • Sarcoidosis is an inflammatory disease characterized by granuloma formation.
    • Hypercalcemia and kidney dysfunction are potential, though less common, manifestations of sarcoidosis.

    Observation:

    • A 56-year-old male presented with hypercalcemia and impaired kidney function.
    • Diagnostic workup revealed elevated 1,25-dihydroxyvitamin D levels and bone marrow findings consistent with granulomatous disease.

    Findings:

    • The diagnosis of sarcoidosis was confirmed by excluding other granulomatous conditions.
    • The patient's hypercalcemia and renal function improved significantly with prednisone treatment.

    Implications:

    • This case highlights the role of autonomous extrarenal production of 1,25-dihydroxyvitamin D in sarcoidosis-related hypercalcemia.

    Related Experiment Videos

  • It underscores the importance of considering sarcoidosis in patients with unexplained hypercalcemia and renal impairment.